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Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 14, 2014; 20(2): 333-345
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.333
Figure 1
Figure 1 Epigenetic regulatory networks in hepatocellular carcinoma. The diagram depicts the composition of polycomb repressive complex 2 (PRC2), which consists of core components EZH1/2, EED, and SUZ12. The PRC2 complex intersects multiple layers of epigenetic regulators to maintain cancer stem cell features, cell proliferation, cell motility and adhesion. The red arrows indicate upregulation of genes, and the green arrows indicate downregulation of genes. LncRNA: Long non-coding RNAs.