Helicobacter pylori eradication and reflux disease onset: Did gastric acid get "crazy"?

Figure 1 Incidence of erosive oesophagitis in Helicobacter pylori eradicated and not eradicated duodenal ulcer patients (Modified from reference 13). The comparable curve slopes would indicate a similar phenomenon. The final difference between patient groups depends on the 1-year delay between curve which remains unexplained. H. pylori: Helicobacter pylori.

Figure 2 The “tale of a crazy acid”. Following Helicobacter pylori gastric in duodenal ulcer patients the hypothesized acid hypersecretion would U-turn into the oesophagus instead of in the duodenal bulb.