Quality of life following laparoscopic Nissen fundoplication: Assessing short-term and long-term outcomes

Figure 1 Change in point prevalence and severity of typical reflux symptoms. A: Patients were assessed for short-term symptoms (n = 247); B: Patients were assessed for long-term symptoms (n = 139); C: Measurement of the changes in long-term moderate to severe symptoms (n = 139). Differences between pre- and post-operative symptoms were significant for heartburn and regurgitation (P < 0.001), late dysphagia (P = 0.016). FU: Follow-up.

Figure 2 Cumulative failure rates for laparoscopic Nissen fundoplication. Surgical failure is shown as a function of time after median follow-up of 10 years (n = 139) (gray part shows 95%CI).

Figure 3 Comparing successful vs failed laparoscopic Nissen fundoplication by rating common gastrointestinal symptoms. A: Gastrointestinal symptom rating scores (GSRS) according to treatment success or failure (dotted line = healthy controls[22]); B: RAND-36 scores according to treatment success or failure (dotted line = age-matched and sex-matched general population[23]). P values were age- and sex-adjusted for treatment success vs failure.