Genetic association of interleukin-6 polymorphism (-174 G/C) with chronic liver diseases and hepatocellular carcinoma

doi:10.3748/wjg.v19.i16.2449

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Apr 28, 2013 (publication date) through Apr 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2013; 19(16): 2449-2455
Published online Apr 28, 2013. doi: 10.3748/wjg.v19.i16.2449

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Figure 1 Interleukin-6 interaction with its receptor complex. A: Mechanism of action of the interleukin-6 (IL-6); B: Activation of the two pathways triggered by the IL-6 action. SHP-2: Src homology 2 domain-containing protein tyrosine phosphatase-2; ERK/MAPK: Extracellular-signal-regulated kinase/mitogen-activated protein kinase; JAK/STAT: Janus associated kinase/signal transducer and activator of transcription.

Citation: Giannitrapani L, Soresi M, Balasus D, Licata A, Montalto G. Genetic association of interleukin-6 polymorphism (-174 G/C) with chronic liver diseases and hepatocellular carcinoma. World J Gastroenterol 2013; 19(16): 2449-2455
URL: https://www.wjgnet.com/1007-9327/full/v19/i16/2449.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i16.2449