Effectiveness of Saccharomyces boulardii in a rat model of colitis

Figure 1 Daily defecation trends, rectal bleeding scores, disease activity index analyses, macro- and microscopic pathological scores of the experimental groups. A: Daily defecation trends; B: Rectal bleeding scores; C: Disease activity index analyses; The results are shown as the mean ± SD. ^aP = 0.018 between trinitrobenzene sulfonic acid (TNBS) and methyl prednisolone (MP) group; ^cP = 0.025 between TNBS and Saccharomyces boulardii (S. boulardii) and TNBS group; D: Macro- and microscopic pathological scores. The results are shown as the mean ± SD. DAI: Disease activity index.

Figure 2 Serum and tissue nitric oxide and tumor necrosis factor-α levels of the experimental groups. A: Serum and tissue nitric oxide levels; B: Serum and tissue tumor necrosis factor (TNF)-α levels. The results are shown as the mean ± SD. ^aP < 0.05 vs Saccharomyces boulardii (S. boulardii) + methyl prednisolone (MP); ^cP < 0.05 vs trinitrobenzene sulfonic acid (TNBS). NO: Nitric oxide.