Gastric mucin expression in Helicobacter pylori-related, nonsteroidal anti-inflammatory drug-related and idiopathic ulcers

Figure 1 Mucin 5AC and mucin 6 expression in gastric ulcers. A: Immunohistochemical stain showing strong expression of mucin 5AC (MUC5AC) in surface and neck cells (× 10) of gastric mucosa from the ulcer edge of a patient with Helicobacter pylori (H. pylori)/non-steroidal anti-inflammatory drugs (NSAID)-negative gastric ulcer; B: Immunohistochemical stain showing strong expression of MUC6 in deep gland cells (× 10) of gastric mucosa from the ulcer edge of a patient with H. pylori/NSAID-negative gastric ulcer; C: Percentage of positive MUCs staining according to H. pylori and NSAID status. Positive stain defined as a stain extent and intensity score product ≥ 2.