Vigorous, but differential mononuclear cell response of cirrhotic patients to bacterial ligands

Figure 1 Receptor expression from peripheral blood mononuclear cells of non-cirrhotic and cirrhotic patients under conditions of non-exposure, lipopolysaccharide or lipoteichoic acid exposure for CD14, toll-like receptor 2 and toll-like receptor 4 expression. Bars represent median values. P < 0.05 denotes statistical significance and P < 0.10 denotes tendency to statistical significance. A: CD14 expression; B: TLR2 expression; C: TLR4 expression. NE: Non-exposure; LPS: Lipopolysaccharide; LTA: Lipoteichoic acid.

Figure 2 Cytokine secretion from peripheral blood mononuclear cells of non-cirrhotic and cirrhotic patients under conditions of non-exposure, lipopolysaccharide or lipoteichoic acid exposure for tumor necrosis factor α, interleukin-1β, interleukin-6, interleukin-12 and interleukin-10 secretion. Bars represent median values. P < 0.05 denotes statistical significance and P< 0.10 denotes tendency to statistical significance. A: Tumor necrosis factor α secretion; B: Interleukin (IL)-1β secretion; C: IL-6 secretion; D: IL-12 secretion; E: IL-10 secretion. NE: Non-exposure; LPS: Lipopolysaccharide; LTA: Lipoteichoic acid.