Decreased IgA+ plasma cells and IgA expression in acute liver necrosis mice

Figure 1 Serum alanine transaminase levels. Each value was expressed as mean ± SE. ^aP < 0.05 vs normal saline (NS). ALT: Alanine transaminase; GalN: Galactosamine; LPS: Lipopolysaccharide.

Figure 2 Hematoxylin and eosin staining of liver tissue (100 ×). A: Normal group; B: Acute liver necrosis group; C: Lipopolysaccharide group; D: Galactosamine group.

Figure 3 Morphology of intestinal samples stained with hematoxylin and eosin (200 ×). A: Normal group; B: Acute liver necrosis group; C: Lipopolysaccharide group; D: Galactosamine group.

Figure 4 Immunoglobulin A+ cells determined by immunohistochemistry (400 ×). Immunohistochemistry demonstrated that Immunoglobulin A in the plasma cells within the lamina propria were stained brown. A: Normal group; B: Acute liver necrosis group; C: Lipopolysaccharide group; D: Galactosamine group.

Figure 5 Immunoglobulin A+ plasma cells (A), the immunoglobulin A expression levels (B) and interferon-γ expression (C) in intestinal mucosal tissue. ^aP < 0.05 vs normal saline (NS). HP: High power field; GalN: Galactosamine; LPS: Lipopolysaccharide.