A rabbit model of pediatric nonalcoholic steatohepatitis: The role of adiponectin

Figure 1 The rabbits fed with the standard diet. A: Normal liver cells without vacuolar degeneration and no distinct inflammatory cell infiltration by HE staining (× 400); B: No positive fat deposition by red-oil staining (× 100); C: Normal liver cells without apparent collagen fibrosis by Masson trichrome staining (× 100).

Figure 2 The rabbits fed with the high-fat diet. A: Pronounced hepatic steatosis. Hepatocellular ballooning with clear vacuolar degeneration was apparent by HE staining (× 400); B: Pronounced hepatic steatosis with positive fat infiltration by red-oil staining (× 200); C: Abundant mononuclear and polymorphonuclear inflammatory cells infiltrates by HE staining (× 400); D: Pieces necrosis by HE staining (× 400); E: Significant collagen and reticulin fibrosis among hepatic cells in blue color by Masson trichrome staining (× 200).