Liver tumor infiltrating lymphocytes: Comparison of hepatocellular and cholangiolar carcinoma

Figure 1 Lymphocytic infiltration in the tumor tissue of hepatocellular carcinoma. A-D: Intratumoral region; E-H: Tumor/liver interface (peritumoral); A and E: CD3+ T cells are the main infiltrate with a higher amount in the interface region; B and F: CD4+ cells were mainly located in the peritumoral area; C and G: In the tumor tissue, CD8+ cells were more often seen; D and H: CD20+ cells were scarce.

Figure 2 The distribution of tumor infiltrating lymphocytes in cholangiocellular carcinoma. A-D: Intratumoral region; E-H: Tumor/liver interface (peritumoral); A and E: CD3+ T cells were the dominant infiltrate; B and F: The quantity of CD4+ and CD8+ cells were opposite with a higher level of CD4 cells in the peritumoral region; C and G: CD8+ cells were more often found in the tumor tissue; D and H: CD20+ cells were scarce.