Expression of thymidylate synthase and glutathione-s-transferase π in patients with esophageal squamous cell carcinoma

Figure 1 Expression of thymidylate synthase (TS) and glutathione-s-transferase π (GST-π) in normal esophageal mucosa and esophageal squamous cell carcinoma. A and E: Negative control for TS and GST-π in normal esophageal mucosa, positive staining can not be detected (using TBS as primary antibody) (× 100); B and F: Positive staining was located in the cytoplasm in normal mucosa (× 200); C and G: Poorly-differentiated SCC, note the diffuse strong TS immunostaining in esophageal SCC (× 200), for GST-π, positive staining was shown in the cytoplasm (× 200); D and H: Moderately-differentiated SCC, TS positive staining is in the cytoplasm (× 200); Well-differentiated SCC, diffuse strong GST-π immunostaining can be seen in esophageal SCC (× 200).