Helicobacter pylori damages human gallbladder epithelial cells in vitro

Figure 1 Culture of normal human gallbladder epithelial cells (HGBEC) (× 400).

Figure 2 Four d after addition of enriched H pylori. A: dead HGBEC (× 400); B: HGBEC characterized by karyopyknosis, vacuoles and incomplete cell structure (× 6000).

Figure 3 Four days after addition of H pylori sonicated extracts. A: Most HGBEC were normal, however, a few HGBEC died (× 400); B: Basically normal HGBEC and some cellular plasm under the vacuole (× 6000).

Figure 4 Effect of different concentrations of H pylori supernatants on ALP, LDH and GGT in the supernatants of HGBEC culture. A: ALP; B: LDH; C: GGT.

Figure 5 Effect of different concentrations of sonicated extracts of H pylori on HGBEC supernatant ALP, LDH and GGT. A: ALP; B: LDH; C: GGT.