Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment

Figure 1 Diagnostic evaluations of recurrent gastrointestinal stromal tumors before starting sunitinib. A: In computed tomography, arrowhead and arrow show metastatic liver mass and colon invasion, respectively. B: In the colonoscopic finding, arrow shows a protruding mass invading from the external lumen.

Figure 2 Diagnostic evaluation of perforating colon in present symptomatic patient during sunitinib treatment. A: In computed tomography, arrow and arrowhead show intraperitoneal free air and the site of colon perforation, respectively. B: In 3-dimensional reconstruction, arrow and arrowhead show the colon lumen and the site of perforation, respectively..

Figure 3 Changes in body temperature and pulse (A) and in neutrophil counts and C-reactive protein (B) of the patient.