Maintenance time of sedative effects after an intravenous infusion of diazepam: A guide for endoscopy using diazepam

Figure 1 Median percent changes from the baseline value (before a diazepam 5 mg infusion) by a critical flicker fusion test (A), a postural sway test (B), and an eye movement test (C) in the 3 different CYP2C19 genotype groups.

Figure 2 Median percent changes from the baseline value [before a diazepam (5-mg) infusion] by a critical flicker fusion test (A), a postural sway test (B), and an eye movement test (C) in all of the enrolled subjects. ^aP < 0.05 by using the Wilcoxon’s signed rank test, when significant differences were obtained by the Friedmann’s test.

Figure 3 Median percent values for mental sedation, “alert to drowsy” (A), “fuzzy to clear-headed” (B), physical sedation, “lethargic to energetic” (C) and “well-coordinated to clumsy” (D) parameters by a VAS symptom assessment test in the 3 different CYP2C19 genotype groups.

Figure 4 Median percent values for mental sedation “alert to drowsy” (A), “muzzy to clear-headed” (B), physical sedation “lethargic to energetic” (C) and “well-coordinated to clumsy” (D) parameters by a VAS symptom assessment test in all of the enrolled subjects. ^aP < 0.05 by using the Wilcoxon’s signed rank test, when significant differences were obtained by the Friedmann’s test.