Liver cell transplantation for Crigler-Najjar syndrome type I: Update and perspectives

Figure 1 Evolution of serum bilirubin before and after LCT in two CN patients performed in our center. A: After fluctuating over a period of 5 yr, serum bilirubin of patient 1 decreased significantly to the lesser value of 11.4 mg/dL in 6 mo. Subsequently, increasing values were observed and the patient was listed for OLT. B: For patient 2, after cell infusions, the serum bilirubin dramatically decreased to the value of 6 mg/dL in 4 mo. At this time, concomitantly to an EBV infection, higher values were observed and the patient underwent OLT. Arrows indicate the timing of cell infusions. TRP: Transplantation.