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Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Mar 21, 2008; 14(11): 1790-1794
Published online Mar 21, 2008. doi: 10.3748/wjg.14.1790
Figure 1
Figure 1 mRNA expression changes of collagen typesIand III, MMP-1, MMP-2, TIMP-1, and TGF-β1 in LX-2 cells after 48 h of treatment with Cpd 861 (0. 01 g/L) or interferon-γ (1 000 000 U/L). The levels of mRNA were determined by real-time PCR and normalized by GAPDH. Results are expressed as fold inductions compared to each control group. The data represent mean ± SE of triplicate for each treatment.
Figure 2
Figure 2 Time course of Cpd 861 on mRNA expressions in LX-2 cells. LX-2 cells were incubated with Cpd 861 (0.01 mg/mL) for 24, 48 and 72 h. The absolute copy number of mRNA for collagen type III, MMP-1, MMP-2, and TIMP-1 was determined by real-time PCR. The data represent mean ± SE of triplicate for each treatment. aP < 0.05 and bP < 0.01 vs LX-2 cell controls.