Alteration of nuclear matrix-intermediate filament system and differential expression of nuclear matrix proteins during human hepatocarcinoma cell differentiation

Figure 1 A: TEM observation of nuclear matrix filaments in SMMC-7721 cells; B: TEM observation of nuclear matrix filaments in SMMC-7721 cells treated with HMBA; C: TEM observation of intermediate filaments in SMMC-7721 cells; D: TEM observation of intermediate filaments in SMMC-7721 cells treated with HMBA; E: TEM observation of NM-IF system in SMMC-7721 cells. L: lamina; NM:Nuclear matrix; IF: intermediate filament; F: TEM observation of NM-IF system in SMMC-7721 cells treated with HMBA. Bar = 0.2 μm.

Figure 2 2-D PAGE gels of nuclear matrix proteins from SMMC-7721 cells, silver stained.

Figure 3 Enlarged maps of changed nuclear matrix proteins from SMMC-7721 cells.

Figure 4 Relative expression level of changed nuclear matrix proteins.