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Copyright ©2007 Baishideng Publishing Group Co.
World J Gastroenterol. May 7, 2007; 13(17): 2427-2435
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2427
Figure 1
Figure 1 Transplantation protocols of three rodents model of HCV infection. A: uPA/SCID model: isolation of human hepatocyte, intrasplenic cell transplantation into homozygous mice and in vivo infection by a HCV positive human serum; B: Trimera model: irradiation and bone marrow reconstitution of mice, transplantation of intrinsically HCV infected human liver fragment or transplantation of an ex vivo pre-infected human liver fragment; C: Rat model: immunotolerisation of foetal rats by in utero injection of Huh7 cells, transplantation in new born rats with the same hepatoma cells and in vivo infection of young chimeric rats by a HCV positive human serum.