Basic Research
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 14, 2006; 12(6): 908-914
Published online Feb 14, 2006. doi: 10.3748/wjg.v12.i6.908
Figure 1
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Figure 1 AST (A) and ALT (B) levels in flushing effluent after 24-h cold storage. UW: liver preserved in UW solution; UW+TMZ: liver preserved in UW with TMZ. aP < 0.05 vs UW.
Figure 2
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Figure 2 AST (A) and ALT (B) levels in perfusate after 30, 60, 90, and 120 min of normothermic reperfusion. UW: liver preserved in UW solution; UW+TMZ: liver preserved in UW with TMZ. aP < 0.05 vs UW.
Figure 3
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Figure 3 Histological change in steatotic and non-steatotic livers after 120 min of normothermic reperfusion. Non-steatotic (A) and steatotic (B) livers preserved in UW solution: Cell swelling and disintegration of hepatic architecture were more evident in steatotic livers. Non-steatotic (C) and steatotic (D) livers preserved in UW solution with TMZ: Hepatic morphology was better preserved in both types of the liver compared to that recorded in UW solution.
Figure 4
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Figure 4 Bile output (A) and percentage of sulfobromophthalein (BSP) in bile (B) of steatotic and non-steatotic livers after 120 min of normothermic reperfusion. UW: livers were preserved in UW solution; UW+TMZ: liver preserved in UW with TMZ. aP < 0.05 vs UW.
Figure 5
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Figure 5 Hepatic malondialdehyde (MDA) levels after 120 min of normothermic reperfusion. UW: liver preserved in UW solution; UW+TMZ: liver preserved in UW with TMZ. aP < 0.05 vs UW.
Figure 6
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Figure 6 Vascular resistance (A) and perfusion flow rate (B) of steatotic and non-steatotic livers after 120 min of normothermic reperfusion. UW: livers were preserved in UW solution; UW+TMZ: liver preserved in UW with TMZ. aP < 0.05 vs UW.
Figure 7
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Figure 7 ATP (A) and adenine nucleotide (B) levels of steatotic and non-steatotic livers after 120 min of normothermic reperfusion. UW: livers were preserved in UW solution; UW+TMZ: liver preserved in UW with TMZ. aP < 0.05 vs UW.
Figure 8
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Figure 8 Electron microscopy analysis of structural integrity of the mitochondria. Non-steatotic (A) and steatotic (B) livers preserved in UW solution: mitochondria swelling and the alterations in the electron density of their matrices were more evident in steatotic livers. Cristae are only seldom visible in steatotic livers. Non-steatotic (C) and steatotic (D) livers preserved in UW solution with TMZ. Mitochondrial integrity was better preserved in both types of liver compared to that recorded in UW solution.