Comparison between bioartificial and artificial liver for the treatment of acute liver failure in pigs

Figure 1 Schematic drawing of our bioartificial liver (BAL) system. It consists of 1 × 10¹⁰ cultured allogeneic hepatocytes in the outer space of a hollow fiber.

Figure 2 Schematic drawing of continuous plasma exchange (CPE) with allogeneic plasma and continuous hemodiafiltration system (CHDF).

Figure 3 Survival after induction of hepatic failure. ^aP < 0.05 vs NT group.

Figure 4 Time transition of the levels of amino acid after induction of acute liver failure in (A) NT group, (B) BAL group and (C) CPE+CHDF group. ^aP < 0.05 vs NT group, ^cP < 0.05 vs NT group and BAL group.

Figure 5 Time transition of the levels of ammonia in the blood after induction of acute liver failure. ^aP < 0.05 vs NT group.

Figure 6 Time transition of the serum levels of (A) potassium and (B) pH after induction of acute liver failure.