Antimicrobial activity of Sapindus mukorossi and Rheum emodi extracts against H pylori: In vitro and in vivo studies

Figure 1 Antibacterial activity of various extracts Sapindus mukorossi and Rheum emodi against S. Aureus (A), B. Subtilis (B),E.Coli (C), P vulgaris (D).

Figure 2 Photograph showing inhibitory activity of S. mukorossi and R. emodi on H pylori. ‘A’ and ‘C’ represents ethanolic and chloroform extracts of S. mukorossi. ‘B’ and ‘D’ represents ethanolic and benzene extracts of R. emodi.

Figure 3 Control Ulcer.

Figure 4 Typical photograph showing gastric biopsy stained with Giemsa Stain showing tufts of spiral shaped H pylori.

Figure 5 Photograph showing colonization of H pylori in the upper gastric and esophageal region.

Figure 6 Typical gel image showing 16S rRNA amplification of H pylori. Lane 1 represents 100bp Molecular weight marker, Lane 2 & 3, 5 & 6, 8 & 9, 11 & 12, 14 & 15 represents 16S rRNA amplification of H pylori DNA isolated from the culture. Lane 17 represents positive control of band at 534 bp. (ATCC26695), Lane 18 represents negative control.

Figure 7 Photograph of gastric mucosal section showing surface erosion and mucous depletion, H pylori can not be seen. Photograph of Post-infection treatment with the extract of Sapindus mukorossi.

Figure 8 Photograph of gastric mucosal section showing small foci surface erosion mucin secreting cells in pits are seen, No H pylori detected. Photograph of Post-infection treatment with the extract of Rheum emodi.

Figure 9 Antibacterial activity of various extracts Sapindus mukorossi and Rheum emodi against H pylori.