Nucleoporin 88 expression in hepatitis B and C virus-related liver diseases

Figure 3 Nuclear Nup88-expression in a DN (A) and in dark brown nuclei of an undifferentiated HCC (B).

Figure 1 Nuclear Nup88 expression (brown nuclei) in non-neoplastic hepatocytes of a liver biopsy with mild unspecific chronic hepatitis (A), weak nuclear expression of Nup88 in chronic HBV-related hepatitis with mild inflammatory changes (B), and moderate nuclear expression of Nup88 in chronic HCV-related hepatitis with mild inflammatory changes (C).

Figure 2 Western blot analysis showing reduced expression of Nup88 in HBV-positive HepG2. 2.15 cells (A) and increased Nup88 expression in HBV-negative HepG2 and HBV-positive HepG2.2.15 (P < 0.002) and HB611 (P < 0.001) cells (B).