Prognostic significance of microsatellite alterations at 1p36 in cholangiocarcinoma

Figure 1 Representative examples of LOH and MSI at various loci of chromosome 1p36 (L, leucocyte DNA; T, tumor DNA). Arrows indicate the abnormalities

Figure 2 LOH and MSI frequencies at each locus of chromosome 1p36-pter.

Figure 3 Fine mapping of the chromosome 1p36-pter in 90 CCA. The common loss regions were located at D1S2845 and the 25.5-cM region between D1S507 and D1S2734.

Figure 4 The Kaplan-Meier survival curves showed a poor prognosis in patients who demonstrated MSI at D1S228. Non informative cases were excluded.