Amplification of D22S283 as a favorable prognostic indicator in liver fluke related cholangiocarcinoma

doi:10.3748/wjg.v12.i27.4338

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Jul 21, 2006 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2006; 12(27): 4338-4344
Published online Jul 21, 2006. doi: 10.3748/wjg.v12.i27.4338

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Figure 1 Percentages of deletion and amplification in each locus.

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Figure 2 Fine mapping of chromosomal region 22q12-qter in CCA from centromeric (NF2) to telomeric (TP) ends. The regions of common amplification are TP, TOB2, and between NF2 and D22S283. The common deleted regions are D22S423 and BIK.

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Figure 3 Survival curve by multivariate Cox regression analysis. A: Multivariate Cox regression analysis revealed D22S283 copy number amplification as an indicator of favorable prognosis; B: blood vessel invasion showed poor prognosis in liver fluke related CCA patients.

Citation: Thanasai J, Limpaiboon T, Jearanaikoon P, Bhudhisawasdi V, Khuntikeo N, Sripa B, Miwa M. Amplification of D22S283 as a favorable prognostic indicator in liver fluke related cholangiocarcinoma. World J Gastroenterol 2006; 12(27): 4338-4344
URL: https://www.wjgnet.com/1007-9327/full/v12/i27/4338.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i27.4338