Genetic instability of BRCA1 gene at locus D17S855 is related to clinicopathological behaviors of gastric cancer from Chinese population

Figure 1 Polyacrylamide gel electrophoresis (PAGE) of BRCA1 gene at D17S855 locus Compared with normal tissue (1N), MSI was positive as added an allele band (↑) in tumor tissue (1C). Compared with normal tissue (2N), LOH was positive as lacked an allele band (↑) in tumor tissue (2C).

Figure 2 The expression of BRCA1 protein in gastric cancer. The brown-yellow granules of BRCA1 protein were mostly located in nucleolus. The cytoplasm and membrane of cells were also stained (HE stained↑). ×100.