Investigation of HER-2 codon 655 single nucleotide polymorphism frequency and c-ErbB-2 protein expression alterations in gastric cancer patients

Figure 1 SNP analysis in (A) chronic gastritis group, and (B) gastric carcinoma group. The SNP in codon 655 of HER-2 was detected in patients No 3, 10, 16, and 18 of gastric carcinoma group (^*). M, molecular weight marker; (-), negative control for PCR; bp, base pair.

Figure 2 Representative images of HER-2 immunoreactivity in (A) moderately differentiated intestinal type adenocarcinoma (score 3), (B) poorly differentiated intestinal type adenocarcinoma (score 3), and (C) chronic gastritis (score 1).