Inter-observer variability in histopathological assessment of liver biopsies taken in a pediatric open label therapeutic program for chronic HBV infection treatment

Figure 1 Observers’ opinions on representativity and technical accuracy of liver biopsy specimens.

Figure 2 Inter-observer agreement in the assessment of liver biopsy specimen representativity and technical accuracy of the slides.

Figure 3 The frequency of different grading and staging scores for individual observer and the mean score frequency for all observers.

Figure 4 The agreement between different observers’ grading and staging score for the same liver biopsy.

Figure 5 Grading and staging dispersion of assessments among different observers (maximal score - minimal score for the same biopsy).