Changes of the gastric endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma: An immunohistochemical quantitative study

Figure 1 CGA-IR cells in the fundus (A, B) and pylorus (C, D) of non-implanted sham (A, B) and 3LL-implanted group (B, D). In 3LL-implanted group, CGA-IR cells dramatically decreased in the both regions of stomach and cells having relative narrow cytoplasm and degranulation were more numerously detected. PAP methods, scale bar = 40 μm.

Figure 2 Somatostatin-IR cells in the fundus (A, B) and pylorus (C, D) of non-implanted sham (A, B) and 3LL-implanted group (B, D). In 3LL-implanted group, somatostatin-IR cells dramatically decreased in both regions of stomach and cells having relative narrow cytoplasm and degranulation were more numerously detected. PAP methods, scale bar = 40 μm.

Figure 3 Serotonin-IR cells in the fundus (A, B) and pylorus (C, D) of non-implanted sham (A, B) and 3LL-implanted group (B, D). In 3LL-implanted group, serotonin-IR cells dramatically decreased in the both regions of stomach and cells having relative narrow cytoplasm and degranulation were more numerously detected. PAP methods, Scale bar = 40 μm.

Figure 4 Gastrin-IR cells in the pylorus of non-implanted Sham (A) and 3LL-implanted group (B). In 3LL-implanted group, Gastrin-IR cells were dramatically decreased in the both regions of stomach and cells having relatively narrow cytoplasm and degranulation were more numerously detected. PAP methods, scale bar = 40 μm.

Figure 5 CCK-8-IR cells in the pylorus of non-implanted sham (A) and 3LL-implanted group (B). Similar shaped and distributions of CCK-8-IR cells were demonstrated between non-implanted Sham and 3LL-implanted group. PAP methods, scale bar = 40 μm.

Figure 6 Glucagon-IR cells in the fundus of non-implanted sham (A) and 3LL-implanted group (B). Similar shaped and distributions of glucagon-IR cells were demonstrated between non-implanted Sham and 3LL-implanted group. PAP methods, scale bar = 40 μm.