Distinct immune response induced by peptidoglycan derived from Lactobacillus sp

Figure 1 General information of gene expression change. A: Distribution of induced (black bars) and repressed genes (gray bars) based on their LSR; B: All induced and repressed genes with absolute value of LSR more than 1 after one and three doses of PG treatment and their intersection. I: One dose of PG treatment. II: Three doses of PG treatment.

Figure 2 Functional profiles of expression changed by PG derived from Lactobacillus sp. in peritoneal macrophages and splenic lymphocytes.

Figure 3 Functional mapping of genes to pathways for products of pro-inflammatory cytokines (A) and IFN-g and T-cell proliferation (B).

Figure 4 In vitro (A) and in vivo (B) inhibitory effects of PG on growth of CT26. Values are mean±SD.

Figure 5 DNA of inoculated colon tumor in 2% agarose gel. Lane 1-3 and 6: control; lane 4: tumor-inoculated mice treated with low doses of PG; lane 5: tumor-inoculated mice treated with high doses of PG.