Amelioration effects of traditional Chinese medicine on alcohol-induced fatty liver

Figure 1 Effect of TCM on concentration of serum TGs (A) and TC (B) of rats fed experimental diet for 10 wk and treated with TCM for the last 4 wk. △, CD; □, ED; ▲, TCM2000; ●, TCM667; ■, TCM222. ^aP<0.05, ^cP<0.05, ^eP<0.05 vs others, ^bP<0.0001 vs control.

Figure 2 Effect of TCM on TGs and TC concentrations in liver of rats fed experimental diet for 10 wk and treated with TCM for the last 4 wk. △, CD; □, ED; ▲, TCM2000; ●, TCM667; ■, TCM222. ^aP<0.05, ^cP<0.05, ^eP<0.05, ^gP<0.05 vs others, ^bP<0.001, ^dP<0.0001 vs control.

Figure 3 Liver histology in rats treated with alcohol or alcohol plus TCM. Frozen sections of liver (×40) taken from (A) CD+saline, (B) ED+saline, (C) ED+TCM2000, (D) ED+TCM667, (E) ED+TCM222-treated rats on 10 wk, (F) densitometer analysis: the representative experiment A–E were quantified and the integrated area were percentized in control rats (100%). In A-E, frozen sections were stained with Oil Red O and counterstained with Mayer’s hematoxylin. Lipid droplets were stained red. ^aP<0.05, ^cP<0.05 vs others.