Detection of lymph nodes micrometastases in Dukes’ A and B colorectal cancer using anti-cytokeratin antibodies AE1/AE3

Figure 1 Representative photographs of micrometastases detected by immunohistochemistry using monoclonal cytokeratin antibody AE1/AE3. A: arrowhead indicates a cancer cell located in the paracortical sinus showing morphological characteristics of malignant cells including a large nucleus and condensed nuclear small body; B: arrowhead points to three cancer cells located in subcapsular sinus. Original magnification: A, ×200; B, ×200.

Figure 2 Representative photographs of micrometastases detected by immunohistochemistry using monoclonal cytokeratin antibody AE1/AE3. A: arrowhead indicates a single cell in the positive node; B: arrowhead shows small groups of cells in the positive node; C: arrowhead points to large tumor deposits in the positive node. Original magnification: A, ×400; B, ×400; C, ×200.