β-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: Relationships with carcinogenesis and metastasis

Figure 1 Immunohistochemical PicTure^TM staining. A: Immunoreactivity of β-catenin was expressed by normal ductal and acinar cells with strong membranous staining at intercellular border, ×100; B and C: Immunoreactivity of β-catenin was mainly located in cytoplasm of PanIN and pancreatic cancer cells, ×200.

Figure 2 Immunohistochemical PicTure^TM staining. A and B: CyclinD1 expression was in the nuclei of PanIN and pancreatic cancer cells, ×200; C and D: c-myc expression located in the nuclei of PanIN and pancreatic cancer cells, ×200.

Figure 3 Immunohistochemical PicTure^TM staining. A and B: The expression of MMP-7 was mainly located in cytoplasm of PanIN and pancreatic cancer cells, ×200. C: Expression of PCNA protein was located in the nuclei of pancreatic cancer cells with brown-yellow granules, ×200.