Connexin 26 correlates with Bcl-xL and Bax proteins expression in colorectal cancer

Figure 1 Immunohistochemical detection of Cx26 in the human colorectal cancer. A and B: Granular staining of Cx26 localized mainly between the colorectal cancer cells in the tumor classified in G2 grade; C: Immunopositive deposits in the form of granules are seen in the normal epithelium adjacent to the tumor; D: Strong cytoplasmic immunostaining of Cx26 in G3 grade colorectal cancer. Original magnification: A, C, and D ×200, B ×400; E: Cytoplasmic localization of Bax immunostaining in colorectal cancer classified as G2 grade; F: Strong cytoplasmic immunostaining of Bax in the majority cells of G3 grade colorectal cancer. Original magnification: E ×100, F ×200; G: Cytoplasmic localization of Bcl-xL immunostaining is focally seen in G2 grade colorectal cancer; H: Strong cytoplasmic immunostaining of Bcl-xL in the majority of colorectal cancer cells. Original magnification: G ×200, H ×100.