Viral Hepatitis
Copyright ©The Author(s) 2004.
World J Gastroenterol. Nov 1, 2004; 10(21): 3137-3140
Published online Nov 1, 2004. doi: 10.3748/wjg.v10.i21.3137
Figure 1
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Figure 1 Partial sequences of plasmids pCMV-S. S2 and pCMV-S.S2+145R A: “↓”± stands for the “G” in gene sequences of pCMV-S.S2 B: “↓”± stands for the “A” in gene sequences of pCMV-S.S2+145R, namely mutant point.
Figure 2
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Figure 2 Secretion of HBsAg in vitro. Series A: HBsAg levels of supernatant collected from pCMV-S.S2 + 145R-transfected cells. Series B: HBsAg levels of supernatant collected from pCMV-S.S2-transfected cells. Series C: Negative control.
Figure 3
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Figure 3 Humoral immune response induced by DNA-based immunization. Series A: Anti-HBs level in pCMV-S.S2-immunized mice. Series B: Anti-HBs level in pCMV-S.S2 + 145R-immunized mice. Series C: Anit-HBs level in pcDNA3.0-immunized mice.
Figure 4
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Figure 4 Comparison of humoral immune responses to preS2 anigen and HBsAg. A: Comparison of humoral immune responses to preS2 anigen. Series a: Anti-preS2 level in pCMV-S.S2-immunized mice. Series b: Anti-preS2 level in pCMV-S.S2 + 145R - immunized mice. Series c: Negative control. B: Comparison of humoral immune responses to HBsAg. Series a: pCMV-S.S2 - immunized mice. Series b: pCMV-S.S2 + 145R-immunized mice. Series c: Negative control.