Electrophysiological effects of anthopleurin-Q on rat hepatocytes

Figure 1 Effects of AP-Q on I_K. A: Family of I_K recorded with changes in the absence or presence of AP-Q 30 nM (upper) and family of I_K recorded with changes after CCl₄ administra-tion in the absence or presence of AP-Q 30 nM (bottom). B: Concentration-response curve for the effects of AP-Q on I_K. n=6. C: I-V relationship of I_K under control (●), AP-Q 30 nM (○), CCl₄ 4 mM (▲) and AP-Q 30 nM after CCl₄ 4 mM administra-tion (△). The voltage steps used to elicit I_K are shown in the inset of panel (B). n=6.