Fecal microbiota transplantation as novel therapy in gastroenterology: A systematic review
Noortje G Rossen, Elisabeth M de Vries, Cyriel Y Ponsioen, Geert R D’Haens, Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, 1105 AZ Amsterdam, The Netherlands
John K MacDonald, Division of Gastroenterology, Robarts Clinical Trials, Robarts Research Institute, The University of Western Ontario, London, Canada and Amsterdam, The Netherlands, Ontario N6A 5K8, Canada
Willem M de Vos, Departments of Bacteriology and Immunology and Veterinary Biosciences, University of Helsinki, FI-00014 Helsinki, Finland
Willem M de Vos, Erwin G Zoetendal, Laboratory of Microbiology, Wageningen University, 6703 HA Wageningen, The Netherlands
Author contributions: Rossen NG and de Vries EM, assessed articles for eligibility in this review; Rossen NG, MacDonald JK and Ponsioen CY prepared the ﬁrst draft of the manuscript; in which MacDonald JK was mainly involved in the method section of this draft; Rossen NG and Ponsioen CY ﬁnalised the manuscript after comments from MacDonald JK, de Vries EM, D’Haens GR, de Vos WM and Zoetendal EG; Rossen NG completed all tables and figures and performed the statistical analyses of the results; all other authors reviewed results, structured and reviewed the manuscript.
Supported by “Dutch Digestive Foundation” Grant 2011 (WO 11-17) (to Rossen NG).
Conflict-of-interest: The authors declare that they have no commercial, personal, political, intellectual, or religious conflict of interest with respect to this manuscript.
Data sharing: Technical appendix, statistical code, and dataset available from the corresponding author at Dryad repository, who will provide a permanent, citable and open-access home for the dataset.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Noortje G Rossen, MD, Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, Room C2-231, 1105 AZ Amsterdam, The Netherlands. email@example.com
Telephone: +31-20-5662199 Fax: +31-20-5669608
Received: September 30, 2014
Peer-review started: September 30, 2014
First decision: October 14, 2014
Revised: November 19, 2014
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 7, 2015