Evolution of disease phenotype in adult and pediatric onset Crohn&rsquo;s disease in a population-based cohort

doi:10.3748/wjg.v19.i14.2217

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2013; 19(14): 2217-2226
Published online Apr 14, 2013. doi: 10.3748/wjg.v19.i14.2217

Evolution of disease phenotype in adult and pediatric onset Crohn’s disease in a population-based cohort

Barbara Dorottya Lovasz, Laszlo Lakatos, Agnes Horvath, Istvan Szita, Tunde Pandur, Michael Mandel, Zsuzsanna Vegh, Petra Anna Golovics, Gabor Mester, Mihaly Balogh, Csaba Molnar, Erzsebet Komaromi, Lajos Sandor Kiss, Peter Laszlo Lakatos

Barbara Dorottya Lovasz, Michael Mandel, Zsuzsanna Vegh, Petra Anna Golovics, Lajos Sandor Kiss, Peter Laszlo Lakatos, First Department of Medicine, Semmelweis University, H-1083 Budapest, Hungary

Laszlo Lakatos, Istvan Szita, Tunde Pandur, Department of Medicine, Csolnoky F Province Hospital, H-8200 Veszprem, Hungary

Agnes Horvath, Department of Pediatrics, Csolnoky F Province Hospital, H-8200 Veszprem, Hungary

Gabor Mester, Mihaly Balogh, Department of Medicine, Grof Eszterhazy Hospital, H-8500 Papa, Hungary

Csaba Molnar, Department of Infectious Diseases, Magyar Imre Hospital, H-8400 Ajka, Hungary

Erzsebet Komaromi, Department of Gastroenterology Municipal Hospital, H-8100 Varpalota, Hungary

Author contributions: Lovasz BD and Lakatos L contributed equally to this work; Lovasz BD contributed to supervision, patient selection and validation, database construction and manuscript preparation; Lakatos L contributed to study design, data collection, supervision, patient selection and validation, database construction, and manuscript preparation; Pandur T, Mester G, Balogh M, Szita I, Molnar C, Komaromi E, Mandel M, Vegh Z, Golovics PA and Kiss LS contributed to database construction and manuscript preparation; Lakatos PL contributed to study design, data collection, supervision, patient selection and validation, database construction, statistical analysis, and manuscript preparation; all authors have approved the final draft submitted.

Supported by Semmelweis University Regional and Institutional Committee of Science and Research Ethics and the Csolnoky F Province Hospital Institutional Committee of Science and Research Ethics

Correspondence to: Peter Laszlo Lakatos, MD, PhD, First Department of Medicine, Semmelweis University, Korányi S. 2/A, H-1083 Budapest, Hungary. lakatos.peter_laszlo@med.semmelweis-univ.hu

Telephone: +36-1-2100278 Fax: +36-1-3130250

Received: November 7, 2012
Revised: November 27, 2012
Accepted: December 20, 2012
Published online: April 14, 2013

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