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World J Gastroenterol. Aug 28, 2012; 18(32): 4288-4299
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4288
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4288
Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis
Sander van der Marel, Anna Majowicz, Karin Kwikkers, Richard van Logtenstein, Sander J van Deventer, Harald Petry, Valerie Ferreira, Department of Research and Development, uniQure B.V., 1105 BA Amsterdam, The Netherlands
Sander van der Marel, Anna Majowicz, Sander J van Deventer, Department of Gastroenterology and Hepatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
Anje A te Velde, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, 1105 BK Amsterdam, The Netherlands
Anne S De Groot, EpiVax Inc., Providence, RI 02903, United States
Anne S De Groot, The Institute for Immunology and Informatics, University of Rhode Island, Kingston, RI 02881, United States
Sybren L Meijer, Department of Pathology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Daniel W Hommes, Center for Inflammatory Bowel Diseases, UCLA Health System, Los Angeles, CA 90095, United States
Author contributions: van der Marel S carried out experiments; van der Marel S and Ferreira V performed literature searches, analyzed the data and wrote the article; Majowicz A, Kwikkers K and van Logtenstein R participated in the experiments; Meijer SL performed histological analysis of colon section; van der Marel S, Majowicz A, Kwikkers K, Logtenstein R, te Velde AA, De Groot AS, Meijer SL, van Deventer SJ, Petry H, Hommes DW and Ferreira V contributed conceptually to the work, reviewed the manuscript and assisted with the editing of the paper.
Supported by Grant from the Broad Medical Research Program of The Broad Foundation, No. IBD-029 5R
Correspondence to: Sander van der Marel, MD, Department of Research and Development, uniQure B.V., Meibergdreef 61, 1105 BA Amsterdam, The Netherlands. s.vandermarel@uniqure.com
Telephone: +31-20-5662053 Fax: +31-20-5669272
Received: June 21, 2012
Revised: August 13, 2012
Accepted: August 16, 2012
Published online: August 28, 2012
Revised: August 13, 2012
Accepted: August 16, 2012
Published online: August 28, 2012
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