Original Article
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Aug 21, 2012; 18(31): 4127-4135
Published online Aug 21, 2012. doi: 10.3748/wjg.v18.i31.4127
siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin
Md. Raghibul Hasan, Shyam Singh Chauhan, Rinu Sharma, Ranju Ralhan
Md. Raghibul Hasan, Shyam Singh Chauhan, Department of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India
Rinu Sharma, Department of Biotechnology, School of Biotechnology, Guru Gobind Singh Indraprastha University, New Delhi 110075, India
Ranju Ralhan, Department of Otolaryngology-Head and Neck Surgery, Joseph and Mildred Sonshine Family Centre for Head and Neck Diseases, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada
Ranju Ralhan, Department of Pathology and Laboratory Medicine, Alex Simona Shnaider Laboratory for Molecular Oncology, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada
Author contributions: Hasan MR designed the study and carried out the experimental procedures, and significantly contributed to the analysis of data and manuscript preparation; Chauhan SS contributed to drafting the manuscript; Sharma R conceptualized and designed the study, contributed in the initial standardization of the RNAi experiments and was involved in interpretation of data and drafting the manuscript; Ralhan R was involved in drafting the manuscript, revising it critically for important intellectual content, and has given approval for the final version; all authors approve the final manuscript.
Supported by Department of Science and Technology, Government of India
Correspondence to: Dr. Rinu Sharma, Assistant Professor, School of Biotechnology, Guru Gobind Singh Indraprastha University, Sector 16 C , Dwarka, New Delhi 110075, India. rinusharma@gmail.com
Telephone: +91-11-25302312 Fax: +91-11-25302111
Received: November 24, 2011
Revised: May 7, 2012
Accepted: May 26, 2012
Published online: August 21, 2012
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