Orotate phosphoribosyl transferase mRNA expression and the response of cholangiocarcinoma to 5-fluorouracil

doi:10.3748/wjg.v18.i30.3955

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2012; 18(30): 3955-3961
Published online Aug 14, 2012. doi: 10.3748/wjg.v18.i30.3955

Orotate phosphoribosyl transferase mRNA expression and the response of cholangiocarcinoma to 5-fluorouracil

Chariya Hahnvajanawong, Jariya Chaiyagool, Wunchana Seubwai, Vajarabhongsa Bhudhisawasdi, Nisana Namwat, Narong Khuntikeo, Banchob Sripa, Ake Pugkhem, Wichittra Tassaneeyakul

Chariya Hahnvajanawong, Jariya Chaiyagool, Department of Microbiology, Center of Excellence for Innovation in Chemistry, and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Wunchana Seubwai, Department of Forensic Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Vajarabhongsa Bhudhisawasdi, Narong Khuntikeo, Ake Pugkhem, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Nisana Namwat, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Banchob Sripa, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Wichittra Tassaneeyakul, Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Author contributions: Tassaneeyakul W and Hahnvajanawong C designed the study, analyzed the data and wrote the paper; Chaiyagool J, Bhudhisawasdi V, Khuntikeo N and Pugkhem A collected the samples; and Hahnvajanawong C, Chaiyagool J, Namwat N, Sripa B and Seubwai W performed the research and analyzed the data.

Supported by The Research Team Strengthening Grant, National Genetic Engineering and Biotechnology Center, National Science and Technology Development Agency, Thailand; The Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Thailand (to Chaiyagool J)

Correspondence to: Chariya Hahnvajanawong, PhD, Assistant Professor, Department of Microbiology, Center of Excellence for Innovation in Chemistry, and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. hchari@kku.ac.th

Telephone: +66-43-363808 Fax: +66-43-363808

Received: December 27, 2011
Revised: May 11, 2012
Accepted: May 26, 2012
Published online: August 14, 2012

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