Copyright
©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Dec 21, 2009; 15(47): 5936-5945
Published online Dec 21, 2009. doi: 10.3748/wjg.15.5936
Published online Dec 21, 2009. doi: 10.3748/wjg.15.5936
Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification
Anna Lyra, Teemu Rinttilä, Lotta Krogius-Kurikka, Erja Malinen, Janne Nikkilä, Laura Mäkelä, Airi Palva, Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki 00014, Finland
Teemu Rinttilä, Alimetrics Ltd., Espoo, Espoo 02920, Finland
Kajsa Kajander, Valio Ltd., Research Centre, Helsinki 00370, Finland; Institute of Biomedicine, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
Jaana Mättö, VTT Biotechnology, VTT, Espoo 02044, Finland; The Finnish Red Cross, Blood Service, Helsinki 00310, Finland
Laura Mäkelä, Institute of Clinical Medicine, University of Helsinki, Helsinki 00014, Finland
Author contributions: Lyra A, Rinttilä T, Krogius-Kurikka L, Kajander K, Malinen E, Mättö J and Palva A designed the research; Lyra A, Rinttilä T, Nikkilä J, Krogius-Kurikka L, Kajander K, Malinen E, Mättö J, Mäkelä L and Palva A took part in writing of the manuscript; Kajander K and Mättö J recruited the study subjects and planned and coordinated collection of samples; Lyra A, Rinttilä T and Mäkelä L designed the qPCR assays; Nikkilä J did the data analysis; Mäkelä L, Krogius-Kurikka L, Lyra A and Rinttilä T performed the experiments; Lyra A wrote the paper.
Supported by The Finnish Funding Agency for Technology and Innovation, Tekes, grants No. 945/401/00 and 40160/05, the Finnish Graduate School of Applied Biosciences, the Academy of Finland, Grant No. 214 157 and the Centre of Excellence on Microbial Food Safety Research, Academy of Finland
Correspondence to: Airi Palva, Professor, Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, University of Helsinki, PO Box 66, Helsinki 00014, Finland. airi.palva@helsinki.fi
Telephone: +358-9-19157058 Fax: +358-9-19157033
Received: August 13, 2009
Revised: September 29, 2009
Accepted: October 6, 2009
Published online: December 21, 2009
Revised: September 29, 2009
Accepted: October 6, 2009
Published online: December 21, 2009
Core Tip