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©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Oct 28, 2009; 15(40): 5058-5066
Published online Oct 28, 2009. doi: 10.3748/wjg.15.5058
Published online Oct 28, 2009. doi: 10.3748/wjg.15.5058
UGT1A1 gene polymorphism: Impact on toxicity and efficacy of irinotecan-based regimens in metastatic colorectal cancer
Christoph Schulz, Volker Heinemann, Andreas Schalhorn, Nikolas Moosmann, Stefan Boeck, Clemens Giessen, Hans-Joachim Stemmler, Department of Haematology & Oncology, Ludwig-Maximilians University of Munich, Campus Grosshadern, Marchioninistr 15, Munich 81377, Germany
Thomas Zwingers, Estimate GmbH, Konrad-Adenauer-Allee 1, Augsburg 86150, Germany
Author contributions: Schulz C and Stemmler HJ contributed equally to this work; Heinemann V and Schalhorn A designed the study; Moosmann N, Boeck S and Giessen C were involved in editing the manuscript; Heinemann V co-ordinated the data collection and its interpretation; Zwingers T provided the statistical analysis; Schulz C and Stemmler HJ analyzed data and wrote the paper.
Correspondence to: Priv.-Doz. Dr. Hans-Joachim Stemmler, Department of Haematology & Oncology, Ludwig-Maximilians University of Munich, Campus Grosshadern, Marchioninistr 15, Munich 81377, Germany. joachim.stemmler@med.uni-muenchen.de
Telephone: +49-89-70956017 Fax: +49-89-70958897
Received: March 26, 2009
Revised: September 27, 2009
Accepted: October 4, 2009
Published online: October 28, 2009
Revised: September 27, 2009
Accepted: October 4, 2009
Published online: October 28, 2009
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