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World J Gastroenterol. Jan 21, 2009; 15(3): 356-365
Published online Jan 21, 2009. doi: 10.3748/wjg.15.356
Genomic-wide analysis of lymphatic metastasis-associated genes in human hepatocellular carcinoma
Chun-Feng Lee, Zhi-Qiang Ling, Ting Zhao, Shih-Hua Fang, Weng-Cheng Chang, San-Chih Lee, Kuan-Rong Lee
Chun-Feng Lee, Kuan-Rong Lee, Institute of Molecular Medicine, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu, Taiwan 300, China
Zhi-Qiang Ling, Zhejiang Academy of Medical Sciences, 182 Tianmushan Road, Hangzhou 310013, Zhejiang Province, China
Ting Zhao, Department of Surgery, Zhejiang Provincial People Hospital, 158, Shangtang Road, Hangzhou 310014, Zhejiang Province, China
Shih-Hua Fang, Institute of Athletics, National Taiwan Sport University, 16, Sec. 1, Shuang-Shih Road, Taichung City, Taiwan 404, China
Weng-Cheng Chang, Graduate Institute of Medical Sciences, Chang Jung Christian University, 396, Chang Jung Road, Sec. 1, Kway Jen, Taiwan 711, China
San-Chih Lee, Department of Nursing, Shu-Zen College of Medicine and Management, 452, Huanciou Road, Lujhu Township, Kaohsiung County, Taiwan 821, China
Author contributions: Lee CF performed most of the experiments, participated in most of the data analysis and drafted the manuscript; Lee KR and Lee SC were the leaders of this project, who conceived the study, designed the research route, guided the experiments and the data analysis, and suggested revisions of the manuscript; Ling ZQ carried out cDNA microarray, real-time RT-PCR experiments and provided critical comments and suggested revisions of the manuscript; Fang SH and Chang WC provided the technique and opinions for this study and also suggested the revisions of the manuscript; Zhao T carried out the hepatocellular carcinoma samples collection and preparation, and participated in parts of experiments. All authors read and approved the final manuscript.
Correspondence to: Kuan-Rong Lee, Institute of Molecular Medicine, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu, Taiwan 300, China. krlee@mx.nthu.edu.tw
Telephone: +86-3-5742755
Fax: +86-3-5715934
Received: October 13, 2008
Revised: December 12, 2008
Accepted: December 19, 2008
Published online: January 21, 2009
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