Viral Hepatitis
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Dec 28, 2008; 14(48): 7335-7344
Published online Dec 28, 2008. doi: 10.3748/wjg.14.7335
Metrically measuring liver biopsy: A chronic hepatitis B and C computer-aided morphologic description
Nicola Dioguardi, Fabio Grizzi, Barbara Fiamengo, Carlo Russo
Nicola Dioguardi, Fabio Grizzi, Carlo Russo, Laboratories of Quantitative Medicine, Istituto Clinico Humanitas IRCCS, Rozzano 20089, Milan, Italy
Barbara Fiamengo, Department of Pathology, Istituto Clinico Humanitas IRCCS, Rozzano 20089, Milan, Italy
Author contributions: Dioguardi N designed and conducted the study, analyzed the data and prepared the manuscript; Grizzi F was responsible for the implementation of the fractal dimension software and for the metric and the immunology of inflammation; Fiamengo B did the anatomical interpretation of the liver biopsy sections; Russo C developed and implemented the computer metrical method.
Supported by Istituto Clinico Humanitas IRCCS, Rozzano, MI, and the “Michele Rodriguez” Foundation - Institute for Quantitative Measures in Medicine, Milan, Italy
Correspondence to: Nicola Dioguardi, MD, Scientific Superintendence, Istituto Clinico Humanitas IRCCS, Via Manzoni 56, Rozzano 20089, Milan, Italy.
Telephone: +39-2-82244501 Fax: +39-2-82244590
Received: July 9, 2008
Revised: August 16, 2008
Accepted: August 23, 2008
Published online: December 28, 2008
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