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World J Gastroenterol. Sep 21, 2008; 14(35): 5419-5427
Published online Sep 21, 2008. doi: 10.3748/wjg.14.5419
Liver insulin-like growth factor 2 methylation in hepatitis C virus cirrhosis and further occurrence of hepatocellular carcinoma
Philippe Couvert, Alain Carrié, Jacques Pariès, Jenny Vaysse, Audrey Miroglio, Antoine Kerjean, Pierre Nahon, Jamel Chelly, Jean-Claude Trinchet, Michel Beaugrand, Nathalie Ganne-Carrié
Philippe Couvert, Alain Carrié, INSERM U551, Dyslipopro-teinemia and Atherosclerosis Research Unit, Paris F-75013, France; Université Paris6, UMR S551, Paris F-75013, France; AP-HP, Groupe hospitalier Pitié Salpétrière, Service de Biochimie endocrinienne et Oncologique, Paris F-75013, France
Jacques Pariès, Department of Public health, Jean Verdier Hospital, AP-HP, Bondy 93140, France
Jenny Vaysse, Department of Biochemistry, Jean Verdier Hospital, AP-HP, Bondy 93140, France
Pierre Nahon, Jean-Claude Trinchet, Michel Beaugrand, Nathalie Ganne-Carrié, Department of Hepato-Gastroenterology, Jean Verdier Hospital, AP-HP, Bondy 93140, France; UPRES EA3409, University Paris 13, Paris F-75651, France
Audrey Miroglio, Antoine Kerjean, Jamel Chelly, Cochin Institut-INSERM-CNRS-University Paris 5-CHU Cochin, Paris 75014, France
Author contributions: Ganne-Carrié N, Trinchet JC, Carrié A and Beaugrand M designed research; Nahon P selected patients; Pariès J analyzed data; Vaysse J tested IGF2 serum level; Couvert P, Kerjean A, Miroglio A and Chelly J performed molecular analyses; Couvert P and Ganne-Carrié N wrote the paper.
Correspondence to: Dr. Nathalie Ganne-Carrié, Department of Hepato-Gastroenterology, Jean Verdier Hospital, AP-HP, Bondy 93140, France. nathalie.ganne@jvr.aphp.fr
Telephone: +33-1-48026296 Fax: +33-1-48026202
Received: May 23, 2008
Revised: July 14, 2008
Accepted: July 21, 2008
Published online: September 21, 2008
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