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©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jun 21, 2008; 14(23): 3662-3671
Published online Jun 21, 2008. doi: 10.3748/wjg.14.3662
Published online Jun 21, 2008. doi: 10.3748/wjg.14.3662
Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status
Pooneh Mokarram, Fakhraddin Naghibalhossaini, Department of Biochemistry, Shiraz University of Medical Sciences, School of Medicine, Shiraz 71345, Iran
Mehdi Saberi Firoozi, Department of Internal Medicine and Gastroenterohepatology Research Centre, Shiraz University of Medical Sciences, Shiraz 71345, Iran
Seyed Vahid Hosseini, Ahmad Izadpanah, Department of Surgery (colorectal ward) and Gastroenterohepatology Research Centre, Shiraz University of Medical Sciences, Shiraz 71345, Iran
Heshmetalah Salahi, Seyed Ali Malek-Hosseini, Department of Surgery and Organ Transplantation Research Centre, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz 71345, Iran
Abdoulrasool Talei, Department of Surgery and Institute of Cancer Research, Shiraz University of Medical Sciences, Shiraz 71345, Iran
Mehra Mojallal, Pathology Laboratory, Dena Hospital, Shiraz 71345, Iran
Author contributions: Naghibalhossaini F designed research and wrote the paper; Hosseini SV, Saberi Firoozi M, Izadpanah A, Salahi H, Malek-Hosseini SA, Talei A, and Mojallal M provided specimens, reagents and analytical tools; Mokarram P performed research.
Correspondence to: Fakhraddin Naghibalhossaini, Department of Biochemistry, Shiraz University of Medical Sciences, School of Medicine, Zand Street, Shiraz 71345, Iran. fakhraddin.naghibalhossaini@elf.mcgill.ca
Telephone: +98-711-2303029
Fax: +98-711-2303029
Received: February 18, 2008
Revised: April 15, 2008
Accepted: April 22, 2008
Published online: June 21, 2008
Revised: April 15, 2008
Accepted: April 22, 2008
Published online: June 21, 2008
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