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Copyright ©2006 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jul 7, 2006; 12(25): 4064-4070
Published online Jul 7, 2006. doi: 10.3748/wjg.v12.i25.4064
Intestinal permeability of metformin using single-pass intestinal perfusion in rats
Nai-Ning Song, Quan-Sheng Li, Chang-Xiao Liu
Nai-Ning Song, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China; National Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China
Quan-Sheng Li, Chang-Xiao Liu, National Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China
Author contributions: All authors contributed equally to the work.
Supported by the National “863” Program of China, No. 2003AA2Z347D and the National “973” Program of China, No. 2004CB518902
Correspondence to: Chang-Xiao Liu, Tianjin Institute of Pharmaceutical Research, 308 An-Shan West Road, Tianjin 300193, China. liuchangxiao@163.com
Telephone: +86-22-23006863
Received: April 14, 2005
Revised: September 5, 2005
Accepted: September 10, 2005
Published online: July 7, 2006
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