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For: Mei Q, Liu Z, Zuo H, Yang Z, Qu J. Idiopathic Pulmonary Fibrosis: An Update on Pathogenesis. Front Pharmacol 2022;12:797292. [PMID: 35126134 PMCID: PMC8807692 DOI: 10.3389/fphar.2021.797292] [Citation(s) in RCA: 148] [Impact Index Per Article: 49.3] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/18/2021] [Accepted: 12/29/2021] [Indexed: 12/15/2022]  Open
Number Cited by Other Article(s)
1
Li D, Qian L, Du Y, Liu L, Sun Z, Han Y, Guo X, Shen C, Zhang Z, Liu X. METTL14-mediated m6A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis. Epigenetics 2025;20:2462898. [PMID: 39916577 PMCID: PMC11810098 DOI: 10.1080/15592294.2025.2462898] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/23/2024] [Revised: 01/01/2025] [Accepted: 01/29/2025] [Indexed: 02/12/2025]  Open
2
Wang Y, Fan W, Guo Y, Sun L, Hu Y, Chen J, Gong L, Xie Z. Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold. Eur J Med Chem 2025;294:117768. [PMID: 40409055 DOI: 10.1016/j.ejmech.2025.117768] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/10/2025] [Revised: 04/23/2025] [Accepted: 05/13/2025] [Indexed: 05/25/2025]
3
Yan L, Li JH, Zhang AL, Li H, Pang B, Meng DY, Fu Q, Du LJ, Su Y. The potential role of biomarkers CD28 and PF4 in the pathogenesis of idiopathic pulmonary fibrosis and their impact on the prognosis: an immune microenvironment analysis. Hereditas 2025;162:98. [PMID: 40483519 PMCID: PMC12144798 DOI: 10.1186/s41065-025-00464-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/27/2025] [Accepted: 05/25/2025] [Indexed: 06/11/2025]  Open
4
Hong J, Pham TX, Lee J, Raslan AA, Nicolas K, Sharov A, Meridew JA, Urrutia RA, Lomberk G, Huang SK, Ligresti G. Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis. Am J Respir Cell Mol Biol 2025;72:627-642. [PMID: 39642371 DOI: 10.1165/rcmb.2024-0255oc] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/31/2024] [Accepted: 12/06/2024] [Indexed: 12/08/2024]  Open
5
Giulianelli G, Cocconcelli E, Fiorentù G, Bernardinello N, Balestro E, Spagnolo P. Idiopathic Pulmonary Fibrosis, Today and Tomorrow: Certainties and New Therapeutic Horizons. Pulm Ther 2025;11:195-234. [PMID: 40323570 PMCID: PMC12102415 DOI: 10.1007/s41030-025-00296-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/27/2025] [Accepted: 04/02/2025] [Indexed: 05/24/2025]  Open
6
Morales EN, Malecki CC, Maruri A, Sánchez VR, Portu A, Goldman A, Chiaramoni NS, Fenoy IM. Preclinical evaluation of N-acetyl-cysteine in association with liposomes of lung surfactant's lipids for the treatment of pulmonary fibrosis and asthma. Toxicol Appl Pharmacol 2025;502:117412. [PMID: 40425069 DOI: 10.1016/j.taap.2025.117412] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/27/2024] [Revised: 05/19/2025] [Accepted: 05/23/2025] [Indexed: 05/29/2025]
7
Zheng S, Zhou Z, Ji J, Liu Y, Jiao X, Li X, Shen Y, Hong H, Han X. M2 macrophage-targeted metal-polyphenol networks (MPNs) for OPN siRNA delivery and idiopathic pulmonary fibrosis therapy. J Control Release 2025;383:113862. [PMID: 40383161 DOI: 10.1016/j.jconrel.2025.113862] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/03/2025] [Revised: 05/11/2025] [Accepted: 05/16/2025] [Indexed: 05/20/2025]
8
Ren C, Zi Y, Zhang X, Liao X, Chen H. Basal and AT2 cells promote IPF-lung cancer co-occurrence via EMT: Single-cell analysis. Exp Cell Res 2025;448:114578. [PMID: 40294812 DOI: 10.1016/j.yexcr.2025.114578] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/16/2025] [Revised: 04/22/2025] [Accepted: 04/25/2025] [Indexed: 04/30/2025]
9
Miao X, Liu P, Liu Y, Zhang W, Li C, Wang X. Epigenetic targets and their inhibitors in the treatment of idiopathic pulmonary fibrosis. Eur J Med Chem 2025;289:117463. [PMID: 40048798 DOI: 10.1016/j.ejmech.2025.117463] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/12/2024] [Revised: 02/24/2025] [Accepted: 02/26/2025] [Indexed: 03/29/2025]
10
Li S, Li C, Sun W, Cao Y, Qi X, Zhang J, Xing Y, Zhou J, Wang L. Spatially Resolved Metabolomics Reveals Metabolic Heterogeneity Among Pulmonary Fibrosis. JOURNAL OF MASS SPECTROMETRY : JMS 2025;60:e5138. [PMID: 40264277 DOI: 10.1002/jms.5138] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 11/27/2024] [Revised: 01/18/2025] [Accepted: 04/02/2025] [Indexed: 04/24/2025]
11
Gao S, Wei Y, Li C, Xie B, Zhang X, Cui Y, Dai H. A novel lncRNA ABCE1-5 regulates pulmonary fibrosis by targeting KRT14. Am J Physiol Cell Physiol 2025;328:C1487-C1500. [PMID: 40111939 DOI: 10.1152/ajpcell.00374.2024] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/03/2024] [Revised: 06/16/2024] [Accepted: 03/03/2025] [Indexed: 03/22/2025]
12
Song L, Gao F, Man J. Ferroptosis: the potential key roles in idiopathic pulmonary fibrosis. Eur J Med Res 2025;30:341. [PMID: 40296070 PMCID: PMC12036158 DOI: 10.1186/s40001-025-02623-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/06/2024] [Accepted: 04/21/2025] [Indexed: 04/30/2025]  Open
13
Li GD, Li J, Fan JQ, Li JY, Zhao B, Chen X. Predictive models and WTAP targeting for idiopathic pulmonary fibrosis (IPF). Sci Rep 2025;15:14622. [PMID: 40287490 PMCID: PMC12033295 DOI: 10.1038/s41598-025-98490-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/29/2024] [Accepted: 04/11/2025] [Indexed: 04/29/2025]  Open
14
Zhou W, Wang J, Ding L, Cai R, Cheng J, Liang P, Zhu Y, Zhang Z. Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF. Sci Rep 2025;15:13805. [PMID: 40258831 PMCID: PMC12012010 DOI: 10.1038/s41598-025-97054-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/22/2024] [Accepted: 04/02/2025] [Indexed: 04/23/2025]  Open
15
Wei Y, Jia Z, Ma J, Zhang W, Li H, Wu J, Wang X, Yu X, Shi Y, Kong X, Pang M. Proteomics and Metabolomics Analyses Reveal a Dynamic Landscape of Coal Workers' Pneumoconiosis: An Insight into Disease Progression. J Proteome Res 2025;24:1715-1731. [PMID: 40036136 PMCID: PMC11976863 DOI: 10.1021/acs.jproteome.4c00715] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2024] [Revised: 02/13/2025] [Accepted: 02/14/2025] [Indexed: 03/06/2025]
16
Huang P, Qin D, Qin Y, Tao S, Liu G. SIRT3/6/7: promising therapeutic targets for pulmonary fibrosis. Front Cell Dev Biol 2025;13:1557384. [PMID: 40241794 PMCID: PMC12000143 DOI: 10.3389/fcell.2025.1557384] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/08/2025] [Accepted: 03/24/2025] [Indexed: 04/18/2025]  Open
17
Liu R, Wu T, Zhou W, Zhu A, Liao W, Ding K. A Novel Polysaccharide from the Flowers of Lilium lancifolium Alleviates Pulmonary Fibrosis In Vivo and In Vitro. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025;73:7774-7787. [PMID: 40114341 DOI: 10.1021/acs.jafc.4c11703] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 03/22/2025]
18
Meshkovska Y, Dzhuraeva B, Godugu C, Pooladanda V, Thatikonda S. Deciphering the interplay: circulating cell-free DNA, signaling pathways, and disease progression in idiopathic pulmonary fibrosis. 3 Biotech 2025;15:102. [PMID: 40165930 PMCID: PMC11954786 DOI: 10.1007/s13205-025-04272-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/12/2024] [Accepted: 03/10/2025] [Indexed: 04/02/2025]  Open
19
Allison MB, Catana C, Zhou IY, Caravan P, Montesi SB. Molecular Imaging of Pulmonary Fibrosis. J Nucl Med 2025;66:502-505. [PMID: 40015916 PMCID: PMC11960603 DOI: 10.2967/jnumed.124.267852] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/31/2024] [Accepted: 02/03/2025] [Indexed: 03/01/2025]  Open
20
Bellani S, Spagnolo P. What rationale for treatment of occupational interstitial lung diseases with the drugs approved for idiopathic pulmonary fibrosis? Curr Opin Allergy Clin Immunol 2025;25:95-104. [PMID: 39680372 DOI: 10.1097/aci.0000000000001055] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/17/2024]
21
Cuadrado A, Cazalla E, Bach A, Bathish B, Naidu SD, DeNicola GM, Dinkova-Kostova AT, Fernández-Ginés R, Grochot-Przeczek A, Hayes JD, Kensler TW, León R, Liby KT, López MG, Manda G, Shivakumar AK, Hakomäki H, Moerland JA, Motohashi H, Rojo AI, Sykiotis GP, Taguchi K, Valverde ÁM, Yamamoto M, Levonen AL. Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases. Redox Biol 2025;81:103569. [PMID: 40059038 PMCID: PMC11970334 DOI: 10.1016/j.redox.2025.103569] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/21/2024] [Revised: 02/13/2025] [Accepted: 02/24/2025] [Indexed: 03/22/2025]  Open
22
Sambataro D, Morina G, Libra A, Palmucci S, Pallotti F, Geraci G, La Rocca G, Ferro F, Moretti M, Baldini C, Vancheri C, Sambataro G. Immunosuppressive Therapy for Usual Interstitial Pneumonia in Autoimmune Rheumatic Diseases: A Review. MEDICINA (KAUNAS, LITHUANIA) 2025;61:599. [PMID: 40282891 PMCID: PMC12028540 DOI: 10.3390/medicina61040599] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 02/28/2025] [Revised: 03/19/2025] [Accepted: 03/23/2025] [Indexed: 04/29/2025]
23
Istifli ES, Netz PA. Interactions of flavonoid and coumarin derivative compounds with transforming growth factor-beta receptor 1 (TGF-βR1): integrating virtual screening, molecular dynamics, maximum common substructure, and ADMET approaches in the treatment of idiopathic pulmonary fibrosis. J Mol Model 2025;31:124. [PMID: 40126695 DOI: 10.1007/s00894-025-06338-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/29/2024] [Accepted: 02/27/2025] [Indexed: 03/26/2025]
24
Shi S, Hong X, Zhang Y, Chen S, Huang X, Zheng G, Hu B, Lu M, Li W, Zhong Y, Sun G, Ouyang Y. Exploring The Role of TOP2A in the Intersection of Pathogenic Mechanisms Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis Based on Bioinformatics. J Inflamm Res 2025;18:3449-3468. [PMID: 40093950 PMCID: PMC11910056 DOI: 10.2147/jir.s497734] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/24/2024] [Accepted: 03/04/2025] [Indexed: 03/19/2025]  Open
25
Sun X, Peng L, Xiao W, Li K, Chen S. Efficacy of ginkgo biloba extract in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2025;16:1524505. [PMID: 40110130 PMCID: PMC11919911 DOI: 10.3389/fphar.2025.1524505] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/07/2024] [Accepted: 02/17/2025] [Indexed: 03/22/2025]  Open
26
Herrmann A, Parr D. Modification of the course of disease progression in idiopathic pulmonary fibrosis by pirfenidone: evidence of the potential for disease reversal. BMJ Case Rep 2025;18:e263966. [PMID: 40032576 DOI: 10.1136/bcr-2024-263966] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 03/05/2025]  Open
27
Ratnasingham M, Bradding P, Roach KM. The role of TRP channels in lung fibrosis: Mechanisms and therapeutic potential. Int J Biochem Cell Biol 2025;180:106728. [PMID: 39672503 DOI: 10.1016/j.biocel.2024.106728] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/26/2024] [Revised: 12/06/2024] [Accepted: 12/10/2024] [Indexed: 12/15/2024]
28
Vithalkar MP, Pradhan S, Sandra KS, Bharath HB, Nayak Y. Modulating NLRP3 Inflammasomes in Idiopathic Pulmonary Fibrosis: A Comprehensive Review on Flavonoid-Based Interventions. Cell Biochem Biophys 2025:10.1007/s12013-025-01696-4. [PMID: 39966334 DOI: 10.1007/s12013-025-01696-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 02/06/2025] [Indexed: 02/20/2025]
29
Tan C, Wang J, Ye X, Kasimu K, Li Y, Luo F, Yi H, Luo Y. Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis. Front Mol Biosci 2025;12:1507163. [PMID: 40034336 PMCID: PMC11872725 DOI: 10.3389/fmolb.2025.1507163] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/07/2024] [Accepted: 01/09/2025] [Indexed: 03/05/2025]  Open
30
Tonello S, D’Onghia D, Di Ruscio A, Mora SM, Vincenzi F, Caria G, Fracchia A, Vercellino N, Bussolati B, Tanzi A, Rizzi M, Minisini R, Sola D, Scacchi M, Mai S, Pirisi M, Smirne C, Grossini E, Cantaluppi V, Comi C, Murdaca G, Colangelo D, Sainaghi PP. Extracellular Vesicles as a Potential Biomarker of Pulmonary Arterial Hypertension in Systemic Sclerosis. Pharmaceuticals (Basel) 2025;18:259. [PMID: 40006072 PMCID: PMC11859480 DOI: 10.3390/ph18020259] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/09/2025] [Revised: 01/28/2025] [Accepted: 02/11/2025] [Indexed: 02/27/2025]  Open
31
Giuliani M, Rizzi A, Pagano M, Raveglia LF, Saccani F, Di Lascia MR, Interlandi M, Nardella TS, Marchini G, Murgo A, Tigli L, Pappani A, Capelli AM, Fernandez SX, Puccini P, Villetti G, Civelli M, Beato C, Moro E, Mundi C, Remelli R, Armani E. Novel Cyclohexyl Amido Acid Antagonists of Lysophosphatidic Acid Type 1 Receptor for the Treatment of Pulmonary Fibrosis. ACS Med Chem Lett 2025;16:317-326. [PMID: 39967626 PMCID: PMC11831564 DOI: 10.1021/acsmedchemlett.4c00559] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Revised: 01/15/2025] [Accepted: 01/17/2025] [Indexed: 02/20/2025]  Open
32
Cheng Y, Jiao Y, Wei W, Kou M, Cai Y, Li Y, Li H, Liu T. FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis. Front Pharmacol 2025;16:1509665. [PMID: 40008127 PMCID: PMC11850536 DOI: 10.3389/fphar.2025.1509665] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/11/2024] [Accepted: 01/08/2025] [Indexed: 02/27/2025]  Open
33
Jin C, Li J, Li Q, Zhang L, Zheng S, Feng Q, Li Y, Zheng Y, Nie Q, Liang J, Wang J. Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease. Front Immunol 2025;16:1458341. [PMID: 39991151 PMCID: PMC11842377 DOI: 10.3389/fimmu.2025.1458341] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/02/2024] [Accepted: 01/14/2025] [Indexed: 02/25/2025]  Open
34
Deng X, Yang Y, Gan L, Duan X, Wang X, Zhang J, Wang A, Zhang A, Yuan Z, Chen D, Zheng A. Engineering Lipid Nanoparticles to Enhance Intracellular Delivery of Transforming Growth Factor-Beta siRNA (siTGF-β1) via Inhalation for Improving Pulmonary Fibrosis Post-Bleomycin Challenge. Pharmaceutics 2025;17:157. [PMID: 40006524 PMCID: PMC11859093 DOI: 10.3390/pharmaceutics17020157] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/27/2024] [Revised: 01/22/2025] [Accepted: 01/22/2025] [Indexed: 02/27/2025]  Open
35
Uhlenbruch M, Polke M, von Eiff D, Koryllos A, Krüger S. The Comorbidity of Lung Cancer and ILD: A Review. Pneumologie 2025. [PMID: 39842452 DOI: 10.1055/a-2512-8349] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/24/2025]
36
Dong S, Fang H, Zhu J, Wu Z, Liu Y, Zhu J, Ma B, Chen Q, Yang Y. Inhalable siRNA Targeting IL-11 Nanoparticles Significantly Inhibit Bleomycin-Induced Pulmonary Fibrosis. ACS NANO 2025;19:2742-2758. [PMID: 39791575 DOI: 10.1021/acsnano.4c15130] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 01/12/2025]
37
Zheng W, Zou M, Hu X, Gao H, Song W, Hou Q, Liu Y, Cheng Z. Human epididymis protein 4-annexin II binding promotes aberrant epithelial-fibroblast crosstalk in pulmonary fibrosis. Commun Biol 2025;8:93. [PMID: 39833358 PMCID: PMC11756390 DOI: 10.1038/s42003-025-07529-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/10/2024] [Accepted: 01/13/2025] [Indexed: 01/22/2025]  Open
38
Du H, Rose JP, Bons J, Guo L, Valentino TR, Wu F, Burton JB, Basisty N, Manwaring-Mueller M, Makhijani P, Chen N, Chang V, Winer S, Campisi J, Furman D, Nagy A, Schilling B, Winer DA. Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes and transcriptomic signatures in human pulmonary fibroblasts. GeroScience 2025:10.1007/s11357-025-01507-x. [PMID: 39826027 DOI: 10.1007/s11357-025-01507-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/20/2024] [Accepted: 12/31/2024] [Indexed: 01/20/2025]  Open
39
Sun W, Zhao B, He Z, Chang L, Song W, Chen Y. PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy. Commun Biol 2025;8:48. [PMID: 39810019 PMCID: PMC11733279 DOI: 10.1038/s42003-024-07334-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/14/2024] [Accepted: 11/29/2024] [Indexed: 01/30/2025]  Open
40
Fischer A, Han W, Hu S, Mück-Häusl M, Wannemacher J, Kadri S, Lin Y, Dai R, Christ S, Su Y, Dasgupta B, Sardogan A, Deisenhofer C, Dutta S, Kadri A, Güney TG, Correa-Gallegos D, Mayr CH, Hatz R, Stoleriu MG, Lindner M, Hilgendorff A, Adler H, Machens HG, Schiller HB, Hauck SM, Rinkevich Y. Targeting pleuro-alveolar junctions reverses lung fibrosis in mice. Nat Commun 2025;16:173. [PMID: 39747171 PMCID: PMC11696612 DOI: 10.1038/s41467-024-55596-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/07/2023] [Accepted: 12/13/2024] [Indexed: 01/04/2025]  Open
41
Choi HK, Bang G, Shin JH, Shin MH, Woo A, Kim SY, Lee SH, Kim EY, Shim HS, Suh YJ, Kim HE, Lee JG, Choi J, Lee JH, Kim CH, Park MS. Regenerative Capacity of Alveolar Type 2 Cells Is Proportionally Reduced Following Disease Progression in Idiopathic Pulmonary Fibrosis-Derived Organoid Cultures. Tuberc Respir Dis (Seoul) 2025;88:130-137. [PMID: 39343426 PMCID: PMC11704724 DOI: 10.4046/trd.2024.0094] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/04/2024] [Revised: 09/14/2024] [Accepted: 09/22/2024] [Indexed: 10/01/2024]  Open
42
Chen L, Hou T, Ge F, Jiang H, Liu F, Tian J, Zheng M. Idiopathic Pulmonary Fibrosis Is Associated With Type 1 Diabetes: A Two-Sample Mendelian Randomization Study. J Gene Med 2025;27:e70008. [PMID: 39822044 DOI: 10.1002/jgm.70008] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/12/2024] [Revised: 12/08/2024] [Accepted: 12/11/2024] [Indexed: 01/19/2025]  Open
43
Xia Y, Zhou F, Hui H, Dai L, Ouyang S. ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target. J Transl Med 2024;22:1114. [PMID: 39707362 DOI: 10.1186/s12967-024-05869-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/09/2024] [Accepted: 11/09/2024] [Indexed: 12/23/2024]  Open
44
Kanaji N, Misaki N, Murota M, Iwata M, Ishikawa R, Yamamura K, Tanaka H, Yokota N, Fujimoto S, Yajima T, Dobashi H, Shimada H, Wakiya R, Watanabe N, Inoue T, Mizoguchi H, Komori Y, Kojima K, Kadowaki N, Dainichi T. Prevalence and clinical features of interstitial lung disease in patients with psoriasis. BMC Pulm Med 2024;24:610. [PMID: 39695614 DOI: 10.1186/s12890-024-03450-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/30/2024] [Accepted: 12/12/2024] [Indexed: 12/20/2024]  Open
45
Singh K, Witek M, Brahmbhatt J, McEntire J, Thirunavukkarasu K, Oladipupo SS. Stage-Dependent Fibrotic Gene Profiling of WISP1-Mediated Fibrogenesis in Human Fibroblasts. Cells 2024;13:2005. [PMID: 39682753 PMCID: PMC11640464 DOI: 10.3390/cells13232005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/03/2024] [Revised: 11/28/2024] [Accepted: 11/29/2024] [Indexed: 12/18/2024]  Open
46
Shin S, Jo H, Agura T, Jeong S, Ahn H, Pang S, Lee J, Park JH, Kim Y, Kang JS. Anti-Inflammatory Effects of Aptamin C in Pulmonary Fibrosis Induced by Bleomycin. Pharmaceuticals (Basel) 2024;17:1577. [PMID: 39770419 PMCID: PMC11676684 DOI: 10.3390/ph17121577] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/17/2024] [Revised: 11/17/2024] [Accepted: 11/20/2024] [Indexed: 01/11/2025]  Open
47
Du H, Rose JP, Bons J, Guo L, Valentino TR, Wu F, Burton JB, Basisty N, Manwaring-Mueller M, Makhijani P, Chen N, Chang V, Winer S, Campisi J, Furman D, Nagy A, Schilling B, Winer DA. Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts. BIORXIV : THE PREPRINT SERVER FOR BIOLOGY 2024:2024.11.18.623471. [PMID: 39605579 PMCID: PMC11601487 DOI: 10.1101/2024.11.18.623471] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Indexed: 11/29/2024]
48
Hou S, Wang X, Guo J, Han Y, You J, Tian Z, Zheng X, Zheng S, Ling Y, Pei L, Wu E. Triangle correlations of lung microbiome, host physiology and gut microbiome in a rat model of idiopathic pulmonary fibrosis. Sci Rep 2024;14:28743. [PMID: 39567656 PMCID: PMC11579350 DOI: 10.1038/s41598-024-80023-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/02/2024] [Accepted: 11/14/2024] [Indexed: 11/22/2024]  Open
49
Araldi GL, Hwang YW, Raghu G. Development and Evaluation of ABI-171, a New Fluoro-Catechin Derivative, for the Treatment of Idiopathic Pulmonary Fibrosis. Int J Mol Sci 2024;25:11827. [PMID: 39519378 PMCID: PMC11546061 DOI: 10.3390/ijms252111827] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/21/2024] [Revised: 10/29/2024] [Accepted: 11/02/2024] [Indexed: 11/16/2024]  Open
50
Gao X, Shao S, Zhang X, Li C, Jiang Q, Li B. Interaction between CD244 and SHP2 regulates inflammation in chronic obstructive pulmonary disease via targeting the MAPK/NF-κB signaling pathway. PLoS One 2024;19:e0312228. [PMID: 39423200 PMCID: PMC11488738 DOI: 10.1371/journal.pone.0312228] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/13/2024] [Accepted: 10/02/2024] [Indexed: 10/21/2024]  Open
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