• Cervical vertebrae
• Chondroma
• Radiculopathy
• Spinal cord
• Spinal neoplasm
• Spinal nerve root
• Vertebral body

• Female
• Humans
• Middle Aged
• Cervical Vertebrae/surgery
• Chondroma/surgery
• Magnetic Resonance Imaging
• Neurosurgical Procedures/methods
• Spinal Neoplasms/surgery
• Spinal Neoplasms/diagnostic imaging
• Treatment Outcome

• University of Lausanne

• Case report
• Common bile duct
• Extrahepatic bile duct
• Immunohistochemistry
• Soft tissue sarcoma
• Undifferentiated pleomorphic sarcoma

• cancer-specific outcome
• neurovascular conservation
• orthopaedics surgery
• soft tissue tumour
• surgical case reports

• Benign
• Myopericytoma
• Tumor
• Ureter

• Gastrointestinal surgery
• Musculoskeletal and joint disorders
• Radiology
• Surgical oncology

• Humans
• Leiomyosarcoma/diagnostic imaging
• Leiomyosarcoma/surgery
• Male
• Perivascular Epithelioid Cell Neoplasms/diagnostic imaging
• Perivascular Epithelioid Cell Neoplasms/surgery
• Retroperitoneal Neoplasms/diagnostic imaging
• Retroperitoneal Neoplasms/surgery
• Retroperitoneal Space/pathology
• Tomography, X-Ray Computed

Liposarcoma is one of the most common adult mesenchymal tumors but is uncommon in the gastrointestinal tract and extremely rare in the stomach. Furthermore, the histological subtypes of liposarcoma usually reported in the stomach are well-differentiated or myxoid, and few reports have been issued on small-sized gastric liposarcomas resected endoscopically and followed up. Herein, we report a case of primary gastric dedifferentiated liposarcoma (DL) that was resected endoscopically.

A 67-year-old female Korean patient was referred to our institution for further evaluation of a gastric submucosal tumor (SMT) located in the lesser curvature of the gastric body by esophagogastroduodenoscopy. Endoscopic ultrasound revealed a well-circumscribed, slightly heterogeneous, isoechoic, 17 mm × 10 mm sized mass originating from the third sonographic layer. Computed tomography showed no evidence of significant lymph node enlargement or distant metastasis. Endoscopic resection was undertaken using the snare resection technique after mucosal precutting to provide a definitive histopathologic diagnosis, which proved to be consistent with DL, based on its morphology and the immunoexpressions of MDM2 and CDK4. The patient was planned for surgery because the deep resection margin was positive for malignancy. After declining any invasive procedure or adjuvant treatment, the patient was placed under close follow-up, and at one year after endoscopic resection, remained disease free.

This is the first reported case of a small primary gastric DL resected endoscopically and followed up. This report demonstrates that when diagnosis of a SMT is uncertain, the use of invasive techniques, including endoscopic resection, should be considered.

• Gastric liposarcoma
• Dedifferentiated liposarcoma
• Submucosal tumor
• Endoscopic resection
• Case report

• Adult
• Aged
• Disease-Free Survival
• Female
• Humans
• Liposarcoma/diagnostic imaging
• Liposarcoma/surgery
• Stomach Neoplasms/diagnostic imaging
• Stomach Neoplasms/surgery
• Tomography, X-Ray Computed

Primitive neuroectodermal tumors are extremely rare and highly aggressive malignant small round cell tumors that arise from the primitive nerve cells of the nervous system or outside it. These tumors share similar histology, immunohistologic characteristics, and cytogenetics with Ewing’s sarcoma. Peripheral primitive neuroectodermal tumors of the chest wall are rare malignant tumors seen in children and young adults.

We report a rare case of peripheral primitive neuroectodermal tumor in a 4-year-old Albanian girl with a mediastinal tumor and an unusual clinical presentation. She was initially treated for acute polyradiculoneuritis (Guillain–Barré syndrome) owing to pain, weakness in the lower limbs, and walking difficulty, as well as severe irritability. During the second week of treatment, the child began to experience dry cough, chest discomfort, and worsening dyspnea. Chest radiography, chest computed tomography, and contrast-enhanced computed tomography demonstrated a large mass in the right hemithorax that was derived from the posterior mediastinum with expansive growth in all directions and that shifted the mediastinal structures in the anterolateral left direction. Consequently, histopathology and immunohistochemical examination of the markers S-100, CD99, and Ki-67 showed that the tumor cells stained positively for S-100 and CD99. The proliferative index measured by Ki-67 was approximately 20%, which suggested primitive neuroectodermal tumor.

Even though other diseases, including leukemia, lymphoma, and neuroblastoma, may be accompanied by musculoskeletal manifestations in children, other solid tumors, such as peripheral primitive neuroectodermal tumors, should be considered in the differential diagnosis in any child presenting with musculoskeletal symptoms.

• Children
• Mediastinal tumor
• Musculoskeletal manifestations
• Primitive neuroectodermal tumor

• Head and neck neoplasms
• STAT6 transcription factor
• immunohistochemistry
• mass excision
• solitary fibrous tumors
• subcutaneous tissue

A 3-year-old spayed female domestic shorthair indoor cat presented with a 3-week history of pain from the pelvic region. Physical examination revealed pain elicited on palpating the pelvic area and right hip. Radiographs and CT showed an expansile, osteolytic process with intact cortex in the right wing of the ilium. CT revealed a monostotic and soft tissue-attenuating process with clear margins. Preoperative histopathological diagnosis of aneurysmal bone cyst was made from incisional biopsies. The cyst was removed en bloc with limb-sparing partial iliectomy. Histopathology confirmed the diagnosis of aneurysmal bone cyst. Recovery from surgery was uneventful. At re-examination 8 weeks and 8 months postoperatively, the cat was pain free and physical examinations were within normal limits.

Feline aneurysmal bone cysts are rare and reported cases are few. To our knowledge, this is the first report describing the CT appearance of a pelvic aneurysmal bone cyst and partial iliectomy with limb preservation in a cat with successful short-term outcome.

• Aneurysmal bone cyst
• CT
• bone cyst
• iliectomy
• internal hemipelvectomy
• limb preservation

•

The preoperative diagnosis of the solitary fibrous tumors is difficult irrespective of usage of the various imaging modalities.

We report two resected cases of solitary fibrous tumors (SFT) that were accidentally found in the pelvic cavity.

Case 1 was a 54-year-old male. A colonoscopy for the examination of intestinal polyps revealed an extramural tumor in the right anterior wall of the low rectum. A preoperative MRI showed a well-demarcated T1 low and T2 mixed intensity extramural tumor (53 × 36 mm) located right lateral to the low rectum and behind the seminal vesicle. Laparoscopic surgery was successful for tumor extirpation. Immunohistochemical examination of the specimen revealed STAT6 (+) and CD34 (+) cells, a Ki67 positivity of 7–8%, a mitotic index of 4–5/50 HPF, and a diagnosis of SFT. There was no recurrence 29 months after surgery. Using RT-PCR and sequencing, we detected the NAB2-STAT6 fusion gene but the locus of genomic inversion was not detected. Case 2 was a 43-year-old male that received conservative treatment for appendicitis. A CT scan accidentally revealed a tumor of 40 mm of length in the left obturator area. A MRI revealed a well-demarcated T1 and T2 high intensity tumor. The patient underwent surgical biopsy. Immunohistochemical examination of the biopsy revealed STAT6 (+) and CD34 (+) cells, Ki67 positive cells < 1%, and a diagnosis of SFT. We could not detect the NAB2-STAT6 fusion gene in the extirpated tumor.

Two cases of pelvic SFT were diagnosed by immunohistochemical examination, RT-PCR and sequencing and successfully resected by laparoscopic surgery.

• Fusion gene
• Laparoscopic surgery
• Pelvic tumor
• STAT6
• Solitary fibrous tumor

• Anatomical site
• Dedifferentiated liposarcoma
• Liposarcoma
• NCDB
• Survivorship

• Adolescent
• Adult
• Age Factors
• Aged
• Cell Differentiation
• Child
• Child, Preschool
• Combined Modality Therapy
• Female
• Humans
• Infant
• Liposarcoma/pathology
• Liposarcoma/therapy
• Male
• Middle Aged
• Neoplasm Grading
• Neoplasm Staging
• Prognosis
• Proportional Hazards Models
• Survival Analysis
• United States