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For: Li L, Yu C. Helicobacter pylori Infection following Endoscopic Resection of Early Gastric Cancer. Biomed Res Int 2019;2019:9824964. [PMID: 31737682 PMCID: PMC6816031 DOI: 10.1155/2019/9824964] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 05/26/2019] [Revised: 07/29/2019] [Accepted: 08/20/2019] [Indexed: 12/14/2022]

For:	Li L, Yu C. Helicobacter pylori Infection following Endoscopic Resection of Early Gastric Cancer. Biomed Res Int 2019;2019:9824964. [PMID: 31737682 PMCID: PMC6816031 DOI: 10.1155/2019/9824964] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 05/26/2019] [Revised: 07/29/2019] [Accepted: 08/20/2019] [Indexed: 12/14/2022]

Number

Cited by Other Article(s)

Lei C, Sun W, Wang K, Weng R, Kan X, Li R. Artificial intelligence-assisted diagnosis of early gastric cancer: present practice and future prospects. Ann Med 2025;57:2461679. [PMID: 39928093 PMCID: PMC11812113 DOI: 10.1080/07853890.2025.2461679] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/08/2024] [Revised: 12/09/2024] [Accepted: 01/23/2025] [Indexed: 02/11/2025] Open

Yanagawa S, Fujikuni N, Tanabe K, Nakahara M, Noriyuki T. The influence of partial gastrectomy for gastric cancer on the spontaneous disappearance of Helicobacter pylori: A single-center prospective study. Cancer Rep (Hoboken) 2023;6:e1903. [PMID: 37697944 PMCID: PMC10728519 DOI: 10.1002/cnr2.1903] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/23/2023] [Revised: 08/02/2023] [Accepted: 08/27/2023] [Indexed: 09/13/2023] Open

Xie B, Xia Y, Wang X, Xiong Y, Chen SB, Zhang J, He WW. Factors associated with heterochronic gastric cancer development post-endoscopic mucosal dissection in early gastric cancer patients. World J Gastrointest Oncol 2023;15:1644-1652. [PMID: 37746653 PMCID: PMC10514730 DOI: 10.4251/wjgo.v15.i9.1644] [Citation(s) in RCA: 2] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/12/2023] [Revised: 08/09/2023] [Accepted: 08/21/2023] [Indexed: 09/13/2023] Open

Zhao X, Zhao R, Feng Y, Qiu Z, Bai X, Zhang D, Zhou Y, Fang H, Liu N, Chen L, Jia C, Yuan Y, Li X, Duan W, Nie G, Hou Y. The roles EpCAM plays to enhance the malignancy of gastric cancer. J Cancer Res Clin Oncol 2023;149:8495-8505. [PMID: 37095412 DOI: 10.1007/s00432-023-04767-2] [Citation(s) in RCA: 2] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2023] [Accepted: 04/08/2023] [Indexed: 04/26/2023]

Jiang S, Ge D, Shou K. Prognosis of patients with early gastric carcinoma treated by endoscopic submucosal dissection and risk factors for additional postoperative surgery. Am J Transl Res 2022;14:3456-3463. [PMID: 35702094 PMCID: PMC9185062] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/29/2021] [Accepted: 01/05/2022] [Indexed: 06/15/2023]

Basso L, Gallo G, Biacchi D, Carati MV, Cavallaro G, Esposito L, Giuliani A, Izzo L, Izzo P, Lamazza A, Polistena A, Tarallo M, Micarelli A, Fiori E. Role of New Anatomy, Biliopancreatic Reflux, and Helicobacter Pylori Status in Postgastrectomy Stump Cancer. J Clin Med 2022;11:1498. [PMID: 35329824 PMCID: PMC8952228 DOI: 10.3390/jcm11061498] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/16/2022] [Revised: 03/06/2022] [Accepted: 03/07/2022] [Indexed: 01/14/2023] Open

Affiliation(s)

Luigi Basso “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Gaetano Gallo Department of Medicine, Surgery and Neurosciences, Operative Unit of General Surgery and Surgical Oncology, University of Siena, 53100 Siena, Italy
Daniele Biacchi “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Maria Vittoria Carati “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Giuseppe Cavallaro “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Luca Esposito “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Andrea Giuliani “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Luciano Izzo “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Paolo Izzo “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Antonietta Lamazza “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Andrea Polistena “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Mariarita Tarallo “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)
Alessandro Micarelli ITER Center for Balance and Rehabilitation Research (ICBRR), 02032 Rome, Italy; Eurac Research, Institute of Mountain Emergency Medicine, 39100 Bolzano, Italy
Enrico Fiori “Pietro Valdoni” Department of Surgery, Policlinico “Umberto I”, “Sapienza” University of Rome, 00161 Rome, Italy; (D.B.); (M.V.C.); (G.C.); (L.E.); (A.G.); (L.I.); (P.I.); (A.L.); (A.P.); (M.T.); (E.F.)

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Mladenova I. Clinical Relevance of Helicobacter pylori Infection. J Clin Med 2021;10:jcm10163473. [PMID: 34441769 PMCID: PMC8396975 DOI: 10.3390/jcm10163473] [Citation(s) in RCA: 36] [Impact Index Per Article: 9.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/14/2021] [Revised: 08/03/2021] [Accepted: 08/04/2021] [Indexed: 12/12/2022] Open

High FAM189B Expression and Its Prognostic Value in Patients with Gastric Cancer. BIOMED RESEARCH INTERNATIONAL 2021;2021:8875971. [PMID: 34124264 PMCID: PMC8172284 DOI: 10.1155/2021/8875971] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 09/14/2020] [Accepted: 04/27/2021] [Indexed: 11/18/2022]

Abstract

The clinical significance of the family with sequence similarity 189 member B (FAM189B) gene remains largely unknown in gastric cancer (GC). A comprehensive investigation combining multiple detection methods was carried out in the current study to unveil the clinical implications and prospective molecular characterization of FAM189B protein and mRNA in GC. The protein level of FAM189B was clearly upregulated in the tumor tissues of GC as compared to noncancerous gastric tissues with 179 GC cases and 147 noncancerous gastric controls assessed by immunohistochemistry. The upregulation of the FAM189B protein was also found in the more deteriorating period of the tumor, as there were increasing trends in the groups of larger tumors, with lymph node metastasis, a further advanced clinical stage, and a higher histological grade. Next, we focused on the mRNA level of FAM189B in GC tissues using various high-throughput data. After the screening of GEO, ArrayExpress, and SRA, we finally achieved 18 datasets, including an RNA sequencing dataset of TCGA. Altogether, 1095 cases of GC tissue samples were collected, with 305 unique examples of noncancerous controls. Concerning the mRNA level of FAM189B in GC, the final standard mean difference (SMD) was 0.46 and the area under the curve (AUC) was 0.79 for the upregulation of FAM189B mRNA, which confirmed that the FAM189B mRNA level was also markedly upregulated in GC tissues and comparable to its protein level. The survival analysis showed that the higher expression of FAM189B was a risk factor for the overall survival, first progression, and postprogression survival of GC. For the Affymetrix ID 1555515_a_at of FAM189B, the higher expression level of FAM189B predicted a lower overall survival, first progression survival, and postprogression survival with the hazard ratio (HR) being 1.56 (1.24, 1.95), 1.69 (1.32, 2.17), and 1.97 (1.5, 2.6), respectively. For the Affymetrix ID 203550_s_at of FAM189B, a similar result could be found with corresponding HR being 1.49 (1.24, 1.8), 1.49 (1.21, 1.83), and 1.66 (1.32, 2.08), respectively. The interaction of MEM, COXPRESdb coexpressed genes, and DEGs of GC finally generated 368 genes, and the pathway of the cell cycle was the top pathway enriched by KEGG. In conclusion, the overexpression of the FAM189B protein and mRNA might enhance the incidence of GC.

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Li F, Wang S, Niu M. Scutellarin Inhibits the Growth and EMT of Gastric Cancer Cells through Regulating PTEN/PI3K Pathway. Biol Pharm Bull 2021;44:780-788. [PMID: 34078809 DOI: 10.1248/bpb.b20-00822] [Citation(s) in RCA: 12] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/22/2022]